Cyanide metabolism and vitamin B12 in multiple sclerosis.

Comparable cases could then only be detected by detailed individual study, as statistical analyses of extensive clinical material would be likely to submerge the rare but significant case. The selectivity of impairment of function demonstrated here must be based on a comparable anatomical differentiation of the neural structures implicated. While information available about the present case permits no speculations in terms of the precise anatomy of the relevant cortical locus, the findings would best be explained on models of cerebral functioning which incorporate the occurrence of certain transformations along anatomically separate and distinctive lines of communication, with the possibility of their selective disconnexion by naturally occurring disease.